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KMID : 0614720020450080972
Journal of Korean Medical Association
2002 Volume.45 No. 8 p.972 ~ p.980
The Usefulness and Current Status of the Screening Program for Early Diagnosis of Hepatocellular Carcinoma


Abstract
The incidence and death rate of hepathocellular carcinoma (HCC) both rank third in Korea (death rate 21.3 per 100,000 in 2000) and HCC is a major health issue in Korea. HCC causes substantial morbidity and mortality and the results of treatments
for
advanced HCC are still disappinting. Considering the high incidence, death rate, and poor prognosis of HCC, it is necessary to establish a national screening program by evaluating the validity. The Korean Association for the Study of the Liver
(KASL)
and National Cancer Center (NCC) cooperatively developed and recently released HCC screening/surveillance recommendation. The target population is patients with chronic hepatits B and C and cirrhosis of any cause, over 30 years of age in male and
40
years of age in female. The surveillance tests consist of serum alpha-fetoprotein and abdominal ultrasonography at least every 6 months. Korean national program for the early detection of cancer will start the HCC screening/surveillance program
in
the
low economic classes from 2003, based on KASL-NCC recommendations. The efficacy of this HCC survaillance program would be worthy of attention.
KEYWORD
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